IL-12/IL-23 p40 antibody (PE)

Catalog No. ABIN2568234

The Rat Monoclonal anti-IL-12/IL-23 p40 antibody has been validated for FACS. It is suitable to detect IL-12/IL-23 p40 in samples from Mouse.

Quick Overview for IL-12/IL-23 p40 antibody (PE) (ABIN2568234)

Target: IL-12/IL-23 p40

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-12/IL-23 p40 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: C17-8

Product Details anti-IL-12/IL-23 p40 Antibody (PE)

Specificity: The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer.

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Target Details for IL-12/IL-23 p40

Target: IL-12/IL-23 p40

Background: The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer. C17.8 seems to neutralize the activity of mouse IL-12 and IL-23. IL-12 is the p70 heterodimer of p35 and p40, expressed by the macrophages, dendritic cells, and monocytes. The C17.8 antibody cross-reacts with IL-23, since IL-23 also contains one p40 subunit.

Gene ID: 16160

UniProt: P43432