Cortisol antibody
Quick Overview for Cortisol antibody (ABIN263582)
Target
See all Cortisol AntibodiesHost
Clonality
Conjugate
Application
Clone
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Characteristics
- Synonyms: Hydrocortisone
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Purification
- Protein G Chromatography.
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Immunogen
- Cortisol-3 (CMO) -BSA. Hybridization of Sp2/0 myeloma cells with spleen cells from Balb/cmice.
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Isotype
- IgG3
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Application Notes
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Can be used in competitive assay of cortisol.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 5.0 mg/mL (OD280nm, E0.1% = 1.4)
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Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
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Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: one year from despatch. -
Expiry Date
- 12 months
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- Cortisol
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Target Type
- Hormone
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Background
- Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.Synonyms: Hydrocortisone
Target
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