Protein Tob1 (TOB1) antibody

Catalog No. ABIN265048

This Rabbit Polyclonal antibody specifically detects Protein Tob1 in WB. It exhibits reactivity toward Human.

Quick Overview for Protein Tob1 (TOB1) antibody (ABIN265048)

Target: Protein Tob1 (TOB1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Specificity: This antibody recognizes TOB1.

Purification: Purified

Immunogen: Synthetic peptide derived from the TOB protein

Isotype: IgG

Application Details

Application Notes: Western Blot: 1 - 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline with 0.08 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Target Details

Target: Protein Tob1 (TOB1)

Alternative Name: TOB1

Background: Rabbit anti-human TOB (Transducer Molecule of erbB-2) reacts with a 45 kDa protein originally identified as a molecule that interacts with the ErbB-2 protein, a receptor protein tyrosine kinase (RPTK). TOB does not contain either SH2 or SH3 domains but is homologous with the N terminus of the anti-proliferative BTG-1 protein. Like BTG-1, TOB when exogenously expressed, is able to suppress the growth of NIH3T3 cells. This growth suppression is hindered by the presence of kinase-active p185erbB2.Synonyms: TOB, TROB1, Transducer of erbB-2 1

Gene ID: 10140

NCBI Accession: NP_005740

UniProt: P50616