PPAP2C
Reactivity: Human
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
Cy3
Application Notes
Western Blot. Enzyme Immunoassay. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
Phosphate buffered saline with 0.08 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Ship on dry ice. Store (in aliquots) at -20 °C to -70 °C.
Target
PPAP2C
(Phosphatidic Acid Phosphatase Type 2C (PPAP2C))
Alternative Name
PPAP2C / LPP2
Background
Phosphatidic acid (PA), lysophosphatidic acid, ceramide 1-phosphate (C1P), and sphingosine 1-phosphate (S1P) are lipid mediators generated by phospholipases, sphingomyelinases, and lipid kinases. The major pathway for degradation of these lipids is dephosphorylation catalyzed by members of two classes (types 1 and 2) of phosphohydrolase activities (PAPs). cDNAs encoding two type 2 PAPs, PAP-2a and -2b, have been expressed by transient transfection and shown to catalyze hydrolysis of PA, C1P, and S1P.Synonyms: Lipid phosphate phosphohydrolase 2, PAP2-gamma, Phosphatidate phosphohydrolase type 2c, Phosphatidic acid phosphatase 2c