CD5L antibody (C-Term)

Catalog No. ABIN265124

The Rabbit Polyclonal anti-CD5L antibody is suitable to detect CD5L in samples from Human and Mouse. It has been validated for WB.

Quick Overview for CD5L antibody (C-Term) (ABIN265124)

Target: CD5L (CD5 Molecule-Like (CD5L))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD5L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD5L Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to CD5L.

Purification: Purified

Immunogen: Rabbit polyclonal AIM antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human AIM.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1 - 2 μg/mL. Positive Control: Expressed in spleen, lymph node, thymus, bone marrow, and fetal liver,but not in non-lymphoid tissue.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Target Details for CD5L

Target: CD5L (CD5 Molecule-Like (CD5L))

Alternative Name: CD5L / API6

Background: Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum -stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.Synonyms: AIM, CD5 antigen-like, CT-2, IgM-associated peptide, SP-alpha

Gene ID: 922

NCBI Accession: NP_005885

UniProt: O43866