Herpes Simplex Virus ICP4 (HSV ICP4) antibody

Antigen: Herpes Simplex Virus ICP4 (HSV ICP4)

Clonality: Monoclonal (H943)

Host: Mouse

Application: Western Blotting (WB), Immunofluorescence (IF)

Catalog no.: ABIN265575

Additional Information

Format: Affinity-purified

Isotype: IgG1 kappa  (Matching secondary antibodies)

Clone: H943

Description: Mouse monoclonal antibody to ICP4 of Herpes Simplex Virus. This antibody originates from ascites fluids and is purified by protein G agarose affinity chromatography

Application Details

Application Notes: Reactive with ICP4 of Herpes Simplex Virus in immunofluorescence (IFA) and western blot at 10 ug/ml.

Concentration: 1.0 mg/ml

Purification: Protein G agarose affinity chromatography

Buffer: Phosphate Buffered Saline pH 7.4 (no azide)

Storage: This product is supplied frozen on dry ice. Upon receipt, store at -20°C. Avoid multiple freeze-thaw cycles as product degradation may result.

Research Area: Virology

Restrictions: For Research Use only

Publications

Publications: Hubenthal-Voss, Houghten, Pereira et al.: "Mapping of functional and antigenic domains of the alpha 4 protein of herpes simplex virus 1." in: Journal of virology, Vol. 62, Issue 2, pp. 454-62, 1988 (PubMed).

Cheshenko, Trepanier, Segarra et al.: "HSV usurps eukaryotic initiation factor 3 subunit M for viral protein translation: novel prevention target." in: PLoS ONE, Vol. 5, Issue 7, pp. e11829, 2010 (PubMed).

Abaitua, Daikoku, Crump et al.: "A single mutation responsible for temperature sensitive entry and assembly defects in the VP1-2 protein of HSV." in: Journal of virology, 2010 (PubMed).

Jambunathan, Chowdhury, Subramanian et al.: "Site-specific proteolytic cleavage of the amino terminus of herpes simplex virus glycoprotein K on virion particles inhibits virus entry." in: Journal of virology, Vol. 85, Issue 24, pp. 12910-8, 2011 (PubMed). Further details: Twelve hours postinfection (hpi), the cells were fixed and stained with anti-ICP4 antibody