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HSV ICP27 antibody

Details for Product No. ABIN265583
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Antigen
Reactivity
Herpes simplex Virus (HSV)
(1)
Host
Mouse
(1)
Clonality (Clone)
Monoclonal ()
Application
Western Blotting (WB), Immunofluorescence (IF)
(1), (1)
Pubmed 6 references available
Quantity 500 µg
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN265583
383.90 $
Plus shipping costs $45.00 and if applicable $26.40 dry ice

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Clone H1113
Isotype IgG1 kappa
Characteristics Mouse monoclonal antibody to ICP27 of Herpes Simplex Virus. This antibody originates from ascites fluids and is purified by protein G agarose affinity chromatography.
Purification Protein G agarose affinity chromatography
Background Herpes simplex virus (HSV) ICP27 (Infected cell polypeptide 27) is an essential and multifunctional regulator of viral gene expression that modulates RNA splicing,polyadenylation, and nuclear export. ICP27 Belongs to the herpes viruses UL69 family. It is involved in the down-regulation of viral immediate-early genes and acts incombination with ICP0 and ICP4 as an activator of late genes. Alternate Names: anti-Herpes simplex virus 1 ICP27 antibody, anti-Herpes simplex virus 1 transcriptional regulator IE63 antibody, anti-Herpes simplex virus 2 ICP27 antibody, anti-Herpessimplex virus 2 transcriptional regulator IE63 antibody
Research Area Virology
Application Notes Reactive with ICP27 of Herpes Simplex Virus in immunofluorescence (IFA) and western blot at 10 ug/ml.
Restrictions For Research Use only
Concentration 1.0 mg/ml
Buffer Phosphate Buffered Saline pH 7.4 (no azide)
Preservative Azide free
Storage -20 °C
Product cited in: Luganini, Nicoletto, Pizzuto et al.: "Inhibition of herpes simplex virus type 1 and type 2 infections by peptide-derivatized dendrimers." in: Antimicrobial agents and chemotherapy, Vol. 55, Issue 7, pp. 3231-9, 2011 (PubMed). (1:200).

Malik, Tabarraei, Kehlenbach et al.: "Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through NUP62, inhibiting host nucleocytoplasmic transport pathways." in: The Journal of biological chemistry, 2012 (PubMed). (1:2000).

Jurak, Silverstein, Sharma et al.: "Herpes Simplex Virus Is Equipped with RNA- and Protein-Based Mechanisms To Repress Expression of ATRX, an Effector of Intrinsic Immunity." in: Journal of virology, Vol. 86, Issue 18, pp. 10093-102, 2012 (PubMed).

Park, Lengyel, Rice: "The role of immediate-early protein ICP27 in the differential sensitivity of herpes simplex viruses type-1 and type-2 to leptomycin B." in: Journal of virology, 2013 (PubMed).

General Salaun, MacDonald, Larralde et al.: "Poly(A)-binding protein 1 partially relocalizes to the nucleus during herpes simplex virus type 1 infection in an ICP27-independent manner and does not inhibit virus replication." in: Journal of virology, Vol. 84, Issue 17, pp. 8539-48, 2010 (PubMed).

Jin, Yan, Ma et al.: "An Herpesvirus Virulence Factor Inhibits Dendritic Cell Maturation Through Protein Phosphatase 1 and I{kappa}B Kinase." in: Journal of virology, 2011 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN265583
383.90 $
Plus shipping costs $45.00 and if applicable $26.40 dry ice

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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