Cytokeratin 18 antibody (Alexa Fluor 594)
-
- Target See all Cytokeratin 18 (KRT18) Antibodies
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This Cytokeratin 18 antibody is conjugated to Alexa Fluor 594
-
Application
- Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 594 under optimal conditions. The solution is free of unconjugated Alexa Fluor® 594.
- Clone
- DA-7
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product KRT18 Primary Antibody
-
anti-Keratin 18 (KRT18) antibody
KRT18 Reactivity: Human WB, FACS, ELISA, IHC (p), IP, ICC Host: Mouse Monoclonal DC-10 unconjugated
anti-Keratin 18 (KRT18) antibodyKRT18 Reactivity: Mammalian WB, FACS, ELISA, IHC (p), IP, ICC Host: Mouse Monoclonal C-04 unconjugated
anti-Keratin 18 (KRT18) (AA 53-150) antibodyKRT18 Reactivity: Human, Mouse, Rat, Pig WB, FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 238-396) antibodyKRT18 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 1-423) antibodyKRT18 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 238-396) antibodyKRT18 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C2 unconjugated
anti-Keratin 18 (KRT18) (AA 102-396) antibodyKRT18 Reactivity: Human WB, IHC, IF, ELISA Host: Rabbit Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 72-380) antibodyKRT18 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 401-430), (C-Term) antibodyKRT18 Reactivity: Human, Mouse WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB18746 unconjugated
anti-Keratin 18 (KRT18) (AA 1-150) antibodyKRT18 Reactivity: Human WB, IHC, FACS, ELISA, ICC Host: Mouse Monoclonal 6G12F2 unconjugated
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Protect from prolonged exposure to light. Do not freeze.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C
-
- Target
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
- Alternative Name
- Cytokeratin 18 (KRT18 Products)
- Background
- Cytokeratin 18, also known as keratin 18, is a type I intermediate filament protein with a molecular weight of approximately 48 kD. Cytokeratin 18 is a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 associates with cytokeratin 8 and is widely expressed in simple epithelial tissues in adults, where it is found in the cytoplasm, nucleus, and nucleolus. Cytokeratin 18 is associated with the cytoskeleton and mutations in this protein have been associated with liver disease after environmental insult. Cytokeratin 18 can be modified by glycosylation, phosphorylation (Ser34 and Ser53), acetylation (Ser2), and proteolytic cleavage at amino acids 238 and 397 by caspase family members. The cytokeratin 18 protein interacts with a number of proteins including caspase 3, 14-3-3 gamma, 14-3-3 zeta, 14-3-3 sigma 14-3-3 beta, 14-3-3 eta, keratin 5, keratin 8, TNF receptor II, plakophilin 2, EGF receptor, and usherin, among others.
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
-
