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CD20 antibody (Alexa Fluor 647)
MS4A1
Reactivity: Human
FACS, IF, IHC, CyTOF, BR
Host: Mouse
Monoclonal
2H7
Alexa Fluor 647
Product Details anti-CD20 Antibody (Alexa Fluor 647)
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Target
See all CD20 (MS4A1) Antibodies
CD20 (MS4A1)
(Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
Reactivity
All reactivities for CD20 antibodies
Human
Host
All hosts for CD20 antibodies
Mouse
Clonality
All clonalities for CD20 antibodies
Monoclonal
Conjugate
All conjugates for CD20 antibodies
This CD20 antibody is conjugated to Alexa Fluor 647
Application
All applications for CD20 antibodies
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Cytometry by Time of Flight (CyTOF), Blocking Reagent (BR)
Cross-Reactivity
Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Pigtailed Macaque, Capuchin Monkey, Squirrel Monkey (Saimiri spec.)
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
2H7
Isotype
IgG2b kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for CD20
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Target
CD20 (MS4A1)
(Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
Alternative Name
CD20 (MS4A1 Products )
Background
CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 Molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
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