CRTAM antibody (APC)

Catalog No. ABIN2658636

Product Details anti-CRTAM Antibody (APC)

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CRTAM antibody is conjugated to APC

Application: Biochemical Assay (BCA)

Purification: The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: Cr24-1

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CRTAM

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Alternative Name: CD355 (CRTAM Products)

Background: CRTAM, (class-I MHC-restricted T-cell associated molecule), is homodimer protein belonging to Ig superfamily. It is expressed transiently on activated NK cells,NKT cells and a subset of CD8+ T cells. Nectin-like molecule-2 (Necl2, TSCL1) is the ligand of CRTAM. CRTAM plays an important role in cell adhesion and migration.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation