CRTAM antibody (AA 260-340)

Catalog No. ABIN7228068

The Rabbit Polyclonal anti-CRTAM antibody (ABIN7228068) specifically detects CRTAM in ELISA and WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for CRTAM antibody (AA 260-340) (ABIN7228068)

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTAM antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CRTAM Antibody

Binding Specificity: AA 260-340

Purpose: Rabbit Anti-CRTAM Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CRTAM protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CRTAM protein at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CRTAM

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Alternative Name: CRTAM

Background: Class-I MHC-restricted T-cell-associated molecule, CD_antigen: CD355CRTAM (Cytotoxic And Regulatory T-Cell Molecule) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Innate Immune System. GO annotations related to this gene include receptor binding. An important paralog of this gene is CADM1. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Molecular Weight: 43kD

Gene ID: 56253

UniProt: O95727

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation