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CD44 antibody (APC-Cy7)

Name: CD44 antibody (APC-Cy7)
SKU: ABIN2660692
Availability: OutOfStock

CD44 Reactivity: Human, Mouse ICFC Host: Rat Monoclonal IM7 APC-Cy7

FACS

1 image

Catalog No. ABIN2660692

Datasheet as PDF

Target See all CD44 Antibodies

CD44
Reactivity
297

135

71

31

25

23

14

13

10

9

8

7

7

5

5

4

2

2

1

1

1

1

1

1
Human, Mouse
Host
178

119

74

1

1

1
Rat
Compatible Secondaries
Clonality
261

110

2
Monoclonal
Conjugate
164

42

31

22

16

7

6

6

5

5

5

4

4

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
This CD44 antibody is conjugated to APC-Cy7
Application
277

147

85

71

70

66

51

41

40

30

26

15

7

6

5

5

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Intracellular Flow Cytometry (ICFC)

Cross-Reactivity

Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Squirrel Monkey (Saimiri spec.), Horse (Equine), Cow (Bovine), Pig (Porcine), Dog (Canine), Cat (Feline)

Purification

The antibody was purified by affinity chromatography, and conjugated with APC/Cy7 under optimal conditions. The solution is free of unconjugated APC/Cy7 and unconjugated antibody.

Clone

IM7

Isotype

IgG2b kappa

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Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Concentration

0.2 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Protect from prolonged exposure to light. Do not freeze.

Storage

4 °C

Storage Comment

The antibody solution should be stored undiluted between 2°C and 8°C.
Target

CD44

Alternative Name

CD44 (CD44 Products)

Background

CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Pathways

Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling