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CD137 antibody
TNFRSF9
Reactivity: Human
FACS
Host: Mouse
Monoclonal
4B4-1
unconjugated
Product Details anti-CD137 Antibody
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Target
See all CD137 (TNFRSF9) Antibodies
CD137 (TNFRSF9)
(Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
Reactivity
All reactivities for CD137 antibodies
Human
Host
All hosts for CD137 antibodies
Mouse
Clonality
All clonalities for CD137 antibodies
Monoclonal
Conjugate
All conjugates for CD137 antibodies
This CD137 antibody is un-conjugated
Application
All applications for CD137 antibodies
Flow Cytometry (FACS)
Cross-Reactivity
Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey
Purification
The antibody was purified by affinity chromatography.
Clone
4B4-1
Isotype
IgG1 kappa
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for CD137
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Target
CD137 (TNFRSF9)
(Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
Alternative Name
CD137 (TNFRSF9 Products )
Background
CDw137 is a 39 kD transmembrane protein also known as 4-1BB. It is expressed on activated T cells. CDw137 is a type I membrane protein and a member of the tumor necrosis factor receptor superfamily. CDw137 appears to be important for T cell proliferation and survival, and induces monocyte activation through its interaction with 4-1BB ligand.
Pathways
Cancer Immune Checkpoints
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