Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC), Neutralization (Neut), Cytometry by Time of Flight (CyTOF)
Purification
The antibody was purified by affinity chromatography.
CD157 is an ectoenzyme member of the ADP-ribosyl cyclase family, also known as ADP-ribosyl cyclase 2, BST-1 (bone marrow stromal cell antigen 1), BP-3 antigen. It has a molecular weight between 40 - 46 kD and is a GPI-linked cell membrane glycoprotein which is expressed as a homodimer. CD157 is expressed by macrophages, neutrophils, bone marrow stromal cells, endothelial cells, follicular dendritic cells, and T and B cell progenitors prior to the rearrangement of the antigen receptors. Besides the ectoenzyme activity, it also plays a role in neutrophil migration and adhesion.