BST1 antibody

Catalog No. ABIN2749045

The Mouse Monoclonal anti-BST1 antibody (Clone SY11B5) (ABIN2749045) specifically detects BST1 in WB, IP, FACS and IHC (fro). The antibody is reactive with Human and Non-Human Primate samples.

Quick Overview for BST1 antibody (ABIN2749045)

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Reactivity: Human, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This BST1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: SY11B5

Product Details anti-BST1 Antibody

Purpose: Anti-Hu CD157 Purified

Cross-Reactivity (Details): Human, Non-Human Primates

Characteristics: The mouse monoclonal antibody SY11B5 recognizes CD157, an approximately 45 kDa GPI-anchored extracellular protein expressed mainly on monocytes, macrophages, granulocytes and bone marrow stromal cells.

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: Human CD157

Isotype: IgG1, kappa

Application Details

Application Notes: Western blotting: Non-reducing conditions.
Immunohistochemistry: Recommended dilution: 5-10 μg/mL.
Flow cytometry: Recommended dilution: 1-12 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for BST1

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Alternative Name: CD157

Background: Bone marrow stromal cell antigen 1,CD157 (cADPr hydrolase 2) is a GPI-anchored ectoenzyme possessing ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activity. It uses NAD and cADP-ribose as substrates. CD157 is expressed on granulocytes, monocytes, macrophages, follicular dendritic cells, bone marrow stromal cells and human umbilical cord vein endothelial cells. In case of rheumatoid arthritis is expression is often higher and it is also differentially expressed in the myeloid leukemias. It may also have a signaling role.,BST1, cADPr hydrolase 2

Gene ID: 683

UniProt: Q10588