CD44 antibody
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- Target See all CD44 Antibodies
- CD44
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Reactivity
- Human, Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD44 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Brand
- Ultra-LEAF™
- Cross-Reactivity
- Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Squirrel Monkey (Saimiri spec.), Horse (Equine), Cow (Bovine), Pig (Porcine), Dog (Canine), Cat (Feline)
- Purification
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
- Clone
- IM7
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product CD44 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Preservative
- Azide free
- Handling Advice
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- CD44
- Alternative Name
- CD44 (CD44 Products)
- Background
- CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
- Pathways
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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