Peripherin (PRPH) antibody
| Antigen |
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| Synonyms |
NEF4, PRPH1, Prph1, Perf, nef4, prph1, MGC69454 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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| Catalog no. |
ABIN271783 |
| Quantity |
100 µg (1,0 mg/ml) (Variants) |
| Price |
340.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: PRPH, NEF4, PRPH1
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Alternative name
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Peripherin
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Swiss-Prot
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P41219
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Cross-Reactivity
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Human, Rat (Rattus)
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Description
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Peripherin is a type III intermediate filament protein that is expressed in peripheral andsome central nervous system (CNS) neurons. Peripherin activation is known to be inducedby leukemia inhibitory factor (LIF). LIF activates Peripherin by inducing members of STATtranscription factor family to bind to a specific promoter element in the Peripherin gene. IL-6 is also known to induce Peripherin expression. Although it is not essential for neuriteformation, peripherin is necessary for cellular intermediate filament network formation. Peripherin, unlike most intermediate filament proteins, has been reported to be modifiedby tyrosine phosphorylation.
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Specificity
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Peripherin (S454) antibody detects endogenous levels of Peripherin protein. Species: Human, Rat. Others not tested.
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Application Notes
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ELISA: 1: 5000~1: 20000. WB: 1: 500~1: 1000. IHC: 1: 50~1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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1,0 mg/ml
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Purification
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Aff - Purified
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Buffer
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Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
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Storage
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Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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Research Area
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Neurology, Cytoskeleton
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Restrictions
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For Research Use only
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Alternatives for antigen "Peripherin (PRPH)", type "Antibodies"
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Hosts
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Rabbit (12), Mouse (10), Chicken (6)
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Reactivities
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Human (14), Mammalian (10), Rat (Rattus) (8), Mouse (Murine) (6), Chicken (4), Cat (Feline) (3), Dog (Canine) (1), Rabbit (1)
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Applications
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Western Blotting (WB) (27), Immunofluorescence (IF) (19), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), Enzyme Immunoassay (EIA) (4), Immunohistochemistry (IHC) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), ELISA (2), ELISA (Detection) (2), Immunocytochemistry (ICC) (1)
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