H/K/N-Ras antibody
| Antigen |
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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| Catalog no. |
ABIN271800 |
| Quantity |
100 µg (1,0 mg/ml) |
| Price |
300.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Cross-Reactivity
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Human, Mouse (Murine), Rat (Rattus)
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Description
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The KRAS gene encodes the human cellular homolog of a transforming gene isolated fromthe Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act asintracellular signal transducers. The most well-studied members of the RAS (derived from'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encodeimmunologically related proteins with a molecular mass of 21 kD and are homologs ofrodent sarcoma virus genes that have transforming abilities. While these wildtype cellularproteins in humans play a vital role in normal tissue signaling, including proliferation,differentiation, and senescence, mutated genes are potent oncogenes that play a role inmany human cancers.
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Specificity
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RASH/RASK (H27) antibody detects endogenous levels of RASH/RASK protein. Species: Human, Mouse, Rat. Others not tested.
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Application Notes
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ELISA: 1: 20000~1: 40000. WB: 1: 500~1: 1000. IHC: 1: 50~1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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1,0 mg/ml
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Purification
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Aff - Purified
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Buffer
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Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
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Storage
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Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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Restrictions
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For Research Use only
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Alternatives for antigen "H/K/N-Ras", type "Antibodies"
