Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) antibody

Antigen: Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7)

Synonyms: D8, UBE2, UBA1B, UBE1L, MGC12713, MOP-4, UBE1L2, FLJ10808, FLJ23367, Uba7, 1300004C08Rik, Ube1l, Ube1l2, RGD1308324, UBA7, UBE1, UBA6, xubc14, ube2s-C, xubc4, ube2d2, ube2d3.1, xubc3

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Catalog no.: ABIN271972

Additional Information

Characteristics: Synonyms: Ubiquitin-activating enzyme 7, UBE2, Ubiquitin-like modifier-activating enzyme 7,Ubiquitin-activating enzyme E1 homolog

Alternative name: UBA7 / UBE1L

Swiss-Prot: P41226

Cross-Reactivity: Human

Description: The ubiquitin activating enzyme E1 (UBE1) catalyzes the first step in ubiquitin conjugationto mark cellular proteins for degradation. UBE1 activates ubiquitin by first adenylating withATP its carboxy-terminal glycine residue and thereafter linking this residue to the sidechain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. UBE1 isan example of an X-Y homologous gene, which is X-linked with a distinct Y-linked gene inmany mammals. However, no UBE1 homolog is detectable on the human Y chromosome. UBE1 is thought to escape X inactivation in humans.

Specificity: UBE1L (E996) antibody detects endogenous levels of UBE1L protein. Species: Human. Others not tested.

Application Details

Application Notes: ELISA: 1: 10000~1: 20000. WB: 1: 500~1: 1000. IHC: 1: 50~1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 1,0 mg/ml

Purification: Aff - Purified

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

Storage: Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Restrictions: For Research Use only