YBX2 antibody
| Antigen |
|
| Clonality |
Polyclonal |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
 Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
|
| Catalog no. |
ABIN272262 |
| Quantity |
100 µg (1.0 mg/ml) |
| Price |
340.00 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Characteristics
|
Synonyms: Contrin, DBPC, CSDA3, MSY2, Y-box-binding protein 2, DNA-binding protein C, Germcell-specific Y-box-binding protein, MSY2 homolog
|
|
Swiss-Prot
|
Q9Y2T7
|
|
Cross-Reactivity
|
Human, Mouse (Murine)
|
|
Description
|
Contrin (MSY2 in mouse) and YB-2 (MSY3/4 in mouse) belong to the Y-box family ofmultifunctional proteins that regulate both transcription and translation. Y-box proteinsinteract with a wide variety of nucleic acid structures to act as transcription factors andmRNA masking proteins. The modular structure of Y-box proteins includes a highlyconserved N-terminal cold-shock domain (CSD, equivalent to the bacterial cold-shockproteins) and four basic C-terminal domains containing arginine clusters and aromaticresidues. MSY2 (Contrin) is a expressed in testis and ovary, where it may represstranslation of parental mRNA. The gene encoding human Contrin maps to chromosome17p11. 2-13. 1. MSY3/4 (YB-2) is also known as DNA binding protein A and is highlyexpressed in testis, heart and muscle. Contrin and YB-2 bind to the consensus sequence5'-UCCAUCA-3' contained in the Y-box element.
|
|
Specificity
|
This antibody detects endogenous levels of MSY2 protein. Species Reactivity: Tested: Human and Mouse.
|
|
Application Notes
|
ELISA: 1/10000~1/20000. Western Blot: 1/500~1/1000. Immunohistochemistry: 1/50~1/200. Immunofluorescence: 1/50~1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
|
|
Concentration
|
1.0 mg/ml
|
|
Purification
|
Aff - Purified
|
|
Buffer
|
Phosphate buffered saline (PBS), pH~7.2 containing 15 mM Sodium Azideas preservative.
|
|
Storage
|
Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "YBX2", type "Antibodies"
