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Antibodies
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anti-Cardiac Troponin I (TNNI3) antibody
Cardiac Troponin I (TNNI3) antibody
| Antigen |
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| Synonyms |
CMH7, RCM1, cTnI, CMD2A, TNNC1, MGC116817, Tn1, LOC397803, TnIc, ctnIc, cmh7, ctni, tnnc1, TNNI3 |
| Clonality |
Monoclonal (C5) |
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Host
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Reactivity
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Human (64), Cow (Bovine) (34), Rabbit (8), Dog (Canine) (7), Cat (Feline) (5), Goat (5), Mouse (Murine) (5), Pig (Porcine) (5), Rat (Rattus) (5), Chicken (2), Fish (2), Mammalian (2), Amphibian (1), Monkey (1)
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Application
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 Alternatives Enzyme Immunoassay (EIA), Western Blotting (WB)
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| Catalog no. |
ABIN272322 |
| Quantity |
1 mg (3.5mg/ml (Sigma protein assay kit)) (Variants) |
| Price |
490.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: TNNI3, TNNC1
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Alternative name
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Cardiac Troponin I (+ skeletal)
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Swiss-Prot
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P19429
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Immunogen
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Free human cardiac troponin I
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Cross-Reactivity
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Amphibian, Cow (Bovine), Chicken, Fish, Human, Mouse (Murine), Rabbit
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Isotype
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IgG2b (Matching secondary antibodies)
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Clone
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C5
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Description
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Troponin I is part of a heteromeric complex playing an important role in the regulation ofskeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI),troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponincomplex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present incardiac muscles in different forms than in skeletal muscles. Only one tissue specificisoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only inmyocardium.
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Specificity
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This antibody reacts equally with free cardiac Troponin I (cTnI) and cTnI forming complexeswith other troponin components. Not affected by heparin, phosphorylation and oxidation. Recognizes an epitope located between amino acid residues 186 and 192 of cTnI. Cross-reacts with skeletal troponin I from human, rat and mouse. Species: Human, Rat, Mouse, Chicken, Bovine, Fish, Rabbit, Amphibian. Others not tested.
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Concentration
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3.5mg/ml (Sigma protein assay kit)
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Purification
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Purified
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Buffer
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PBS, pH 7.4 containing 0,09% sodium azide
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Storage
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Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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Research Area
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Serum/Plasma Proteins
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Restrictions
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For Research Use only
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Alternatives for antigen "Cardiac Troponin I (TNNI3)", type "Antibodies"
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Hosts
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Mouse (81), Goat (7), Rabbit (5)
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Reactivities
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Human (64), Cow (Bovine) (34), Rabbit (8), Dog (Canine) (7), Cat (Feline) (5), Goat (5), Mouse (Murine) (5), Pig (Porcine) (5), Rat (Rattus) (5), Chicken (2), Fish (2), Mammalian (2), Amphibian (1), Monkey (1)
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Applications
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Western Blotting (WB) (78), Immunohistochemistry (Frozen Sections) (IHC (fro)) (59), Immunoprecipitation (IP) (59), Enzyme Immunoassay (EIA) (55), ELISA (Detection) (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), ELISA (Capture) (5), ELISA (2), Immunohistochemistry (IHC) (2), Radioimmunoassay (RIA) (2)
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Epitopes
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AA 1-23 (1), AA 117-126 (1), AA 143-152 (1), AA 148-158 (1), AA 27-39 (1), AA 65-74 (1), AA 69-86 (1)
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