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CD2 antibody (PE)

CD2 Reactivity: Human FACS Host: Mouse Monoclonal MEM-65 PE
Catalog No. ABIN272342
  • Target See all CD2 Antibodies
    CD2
    Reactivity
    • 157
    • 35
    • 22
    • 15
    • 12
    • 10
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 130
    • 47
    • 25
    • 1
    Mouse
    Clonality
    • 156
    • 43
    • 4
    Monoclonal
    Conjugate
    • 96
    • 22
    • 22
    • 16
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD2 antibody is conjugated to PE
    Application
    • 147
    • 53
    • 51
    • 38
    • 33
    • 31
    • 20
    • 15
    • 14
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Clone
    MEM-65
    Isotype
    IgG1
    Top Product
    Discover our top product CD2 Primary Antibody
  • Application Notes
    Flow Cytometry analysis of blood cells using 20 m l reagent / 100 m l of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody at 2 - 8 °C. DO NOT FREEZE! Centrifuge vial before opening. This product is photosensitive and should be protected from light.
    Shelf Life: one year from despatch.
    Expiry Date
    12 months
  • Target
    CD2
    Alternative Name
    CD2 (CD2 Products)
    Background
    CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Morover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.Synonyms: Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5
    UniProt
    P06729
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