CD2 antibody (FITC)

Catalog No. ABIN125760

Cited in 1 publication. The FITC-conjugated Mouse Monoclonal anti-CD2 antibody (Clone LT2) (ABIN125760) specifically detects CD2 in FACS. The antibody is reactive with Human samples.

Quick Overview for CD2 antibody (FITC) (ABIN125760)

Target: CD2

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD2 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: LT2

Product Details anti-CD2 Antibody (FITC)

Purpose: Anti-Hu CD2 FITC

Cross-Reactivity (Details): Human

Characteristics: The antibody LT2 reacts with an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.

Purification: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Normal human blood lymphocytes.

Isotype: IgG2b

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze,Protect from prolonged exposure to light

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

References for anti-CD2 antibody (FITC) (ABIN125760)

Gannon, Rhind, Suzui, Zamecnik, Sabiston, Shek, Shephard: "beta-Endorphin and natural killer cell cytolytic activity during prolonged exercise. is there a connection?" in: The American journal of physiology, Vol. 275, Issue 6 Pt 2, pp. R1725-34, (1999) (PubMed).

Target Details for CD2

Target: CD2

Alternative Name: CD2

Background: CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC

Gene ID: 914

UniProt: P06729