CD74 antibody

Catalog No. ABIN284310

Product Details anti-CD74 Antibody

Target: CD74 (HLA-DR-gamma (CD74))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD74 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Purity: > 95 % pure

Immunogen: CD74 antibody was raised in mouse using RPMI 1788 Cell line as the immunogen.

Clone: M-B741

Isotype: IgG2a

Application Details

Application Notes: FC: 5 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

This antibody recognizes the CD74 molecule of about 33 kDa.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM Na0 O4, pH 7.5, with 100 M KCL, 150 M NaCl, and 0.5 mg/mL gentamycin sulfate.

Preservative: Gentamicin sulfate

Precaution of Use: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C

References for anti-CD74 antibody (ABIN284310)

Baugh, Black, Westwood, Kinghorn, McGregor, Bruin, Hamilton, Dempster, Claxton, Cai, Bennett, Long, McKinnon, Vink, den Hoed, Gorecka, Vora, Grant, Percival, Boots, van Lierop: "Therapeutic dosing of an orally active, selective cathepsin S inhibitor suppresses disease in models of autoimmunity." in: Journal of autoimmunity, Vol. 36, Issue 3-4, pp. 201-9, (2011) (PubMed).

Target Details for CD74

Target: CD74 (HLA-DR-gamma (CD74))

Alternative Name: CD74 (CD74 Products)

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints