Protease antibody

Catalog No. ABIN284976

The Rabbit Polyclonal anti-Protease antibody (ABIN284976) specifically detects Protease in ELISA and WB. The antibody is reactive with Human Immunodeficiency Virus (HIV) samples.

Quick Overview for Protease antibody (ABIN284976)

Target: Protease

Reactivity: Human Immunodeficiency Virus (HIV)

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details

Purification: Purified

Purity: > 95 % pure

Immunogen: HIV1 protease antibody was raised in rabbit using full length recombinant protease (HIV-1) as the immunogen.

Isotype: IgG

Application Details

Application Notes: ELISA: 1:500-1:1,000, WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Frozen

Concentration: Lot specific

Buffer: Supplied frozen in PBS.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -70 °C for long term storage.

Target Details

Target: Protease

Target Type: Viral Protein

Background: HIV-1 protease (HIV PR) is a retroviral aspartyl protease that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV PR cleaves newly synthesized polyproteins at the appropriate places to create the mature protein components of an infectious HIV virion. Without effective HIV PR, HIV virions remain uninfectious. Thus, mutation of HIV PR’s active site or inhibition of its activity disrupts HIV’s ability to replicate and infect additional cells, making HIV PR inhibition the subject of much pharmaceutical research.