PDGF antibody

Antigen: PDGF

Clonality: Polyclonal

Host: Goat

Application: Western Blotting (WB)

Catalog no.: ABIN285887

Additional Information

Immunogen: PDGF antibody was raised in goat using purified human PDGF-AB as the immunogen.

Isotype: IgG  (Matching secondary antibodies)

Description: Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.

Specificity: Pocine and bovine PDGF may be detected with decreased in sensitivity. Rodent PDGF will not be detected. This antibody will neutralize human, porcine, bovine and rodent PDGF.

Molecular Weight: 14-16 kDa (predicted detection band MW)

Application Details

Concentration: Batch dependent - please inquire should you have specific requirements

Purification: PDGF antibody was purified by DEAE chromatgraphy.

Buffer: Affi-Gel Blue purified protein supplied in 0.1M tris-glycine, pH 7.0.

Storage: Aliquot and store at -20 °C. Avoid repeated Freeze/Thaw cycles