RANKL antibody (Biotin)

Catalog No. ABIN288465

The Biotin-conjugated Goat Polyclonal anti-RANKL antibody (ABIN288465) specifically detects RANKL in WB, ELISA and InhibAb. The antibody is reactive with Human samples.

Quick Overview for RANKL antibody (Biotin) (ABIN288465)

Target: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This RANKL antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Blocking Antibody (InhibAb)

Product Details anti-RANKL Antibody (Biotin)

Immunogen: sRANKL antibody (biotin) was raised in goat using highly pure recombinant human sRANKL as the immunogen.

Application Details

Application Notes: ELISA: 0.25-1 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute to a concentration of 50 µg/mL with sterile PBS solution containing 0.1 % BSA.

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for RANKL

Target: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Alternative Name: sRANKL

Background: RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate naïve T-cell proliferation in a mixed lymphocyte reaction, to promote the survival of RANK + T cells, and to regulate T-cell-dependent immune response.

Pathways: NF-kappaB Signaling