CD11c antibody
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- Target See all CD11c (ITGAX) Antibodies
- CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD11c antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- Specificity
- Recognizes human CD11c, otherwise known as integrin alpha X chain and leukocyte adhesion receptor p150,95, a 150kD type I transmembrane protein and member of the integrin alpha chain family, expressed by monocytes, macrophages, granulocytes and NK cells, and is a marker for hairy cell leukaemia cells. CD11c combines with the CD18 beta chain (ITGB2) to form the leukocyte specific integrin CR4, acts as a mediator of leukocyte adherence to endothelium, and binds to the ligands CD54 (ICAM1), iC3b and fibrinogen. Clone CBR-p150/4G1 inhibits the binding of CD11c to endothelial cells. Does not recognize CD11a, CD11b or CD18.
- Purification
- Affinity purified
- Immunogen
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Recombinant human CD11c.
Type of Immunogen: Recombinant protein - Clone
- CBR-p150-4G1
- Isotype
- IgG2a
- Top Product
- Discover our top product ITGAX Primary Antibody
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- Application Notes
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Approved: Flo, Func, IHC, IHC-Fr (5 - 10 μg/mL), IP
Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS.
- Preservative
- Azide free
- Storage
- -20 °C
- Storage Comment
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Short term: -20°C
Long term: -20°C.
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- Target
- CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
- Alternative Name
- ITGAX / CD11c (ITGAX Products)
- Background
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Name/Gene ID: ITGAX
Family: Integrin
Synonyms: ITGAX, CD11c antigen, Integrin alpha-X, Leu M5, alpha subunit, p150 95 integrin alpha chain, SLEB6, CD11C, Leu M5 - Gene ID
- 3687
- UniProt
- P20702
- Pathways
- Complement System, Activated T Cell Proliferation, Integrin Complex
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