SIRPG antibody
Quick Overview for SIRPG antibody (ABIN298912)
Target
See all SIRPG AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Recognizes human SIRP gamma, a 55kD signal regulatory protein which is a member of the immunoglobulin gene superfamily. SIRP gamma, also known as CD172g, is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. It is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.
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Purification
- Affinity purified
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Immunogen
- Purified recombinant SIRPgamma. CD4.
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Isotype
- IgG1
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Application Notes
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Approved: Flo (1:50 - 1:200), IP
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short term: 4°C
Long term: -20°C.
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- SIRPG (Signal-Regulatory Protein gamma (SIRPG))
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Alternative Name
- SIRPG
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Background
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Name/Gene ID: SIRPG
Synonyms: SIRPG, BA77C3.1, CD172g antigen, CD172g, SIRP beta 2, SIRP-beta-2, SIRP-gamma, SIRPgamma, SIRP-B2 -
Gene ID
- 55423
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UniProt
- Q9P1W8
Target
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