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Antibody
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anti-Signal Transducer CD24 CD24
Signal Transducer CD24 (CD24) antibody
| Antigen |
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| Synonyms |
CD24A, FLJ22950, FLJ43543, MGC75043 |
| Clonality |
Monoclonal (SN3) |
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Host
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Reactivity
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Application
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 Alternatives Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
Flow Cytometry (FACS) (155), Immunohistochemistry (Frozen Sections) (IHC (fro)) (46), Western Blotting (WB) (37), Enzyme Immunoassay (EIA) (20), Immunofluorescence (IF) (19), Immunoprecipitation (IP) (17), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (14), ELISA (8), Dot Blot (Dot) (4), ELISA (Detection) (3), Immunohistochemistry (IHC) (3), Immunocytochemistry (ICC) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Capture) (1), Functional Studies (Func) (1), Immunoelectron Microscopy (EM) (1), Radioimmunoassay (RIA) (1)
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| Catalog no. |
ABIN302076 |
| Quantity |
0.1 mg (1 mg/ml) |
| Price |
312.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 3 to 5 Business days |
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Alternative name
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CD24
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Immunogen
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Glycoproteins purified from human NALM-1 cell line.
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Format
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Purified
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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SN3
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Description
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CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-likeGPI-anchored extracellular membrane glycoprotein expressed on several cell types,including B cells. When B cells are activated and induced to further maturation, however,CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, therebyregulating the activity of integrins and other proteins such as the chemokine receptorCXCR4, it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cellprecursors but not in mature resting B cells, where it instead inhibits their ability to proliferatein response to activation. CD24 expression is associated with invasiveness and poorerprognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.
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Specificity
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The antibody SN3 reacts with CD24, a 35-45 kDa heavily glycosylated cell surface antigen.CD24 is expressed by granulocytes, B lymphocytes and by some activated T cells and T cellmalignancies. It is not expressed on human thymocytes.HLDA IV, WS Code B 136HLDA V, WS Code B CD24.7
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Application Notes
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Immunohistochemistry (frozen sections) - Positive tissue: tonsil
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Concentration
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1 mg/ml
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Purity
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> 95% (by SDS-PAGE)
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Purification
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Purified from hybridoma culture supernatant by protein-G affinity chromatography.
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Buffer
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Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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Storage
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Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles.
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Research Area
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CD Antigens, Surface Receptors of Immune Cells
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Restrictions
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For Research Use only
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Alternatives for antigen "Signal Transducer CD24 (CD24)", type "Antibodies"
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Hosts
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Mouse (95), Rat (71), Rabbit (23), Chicken (2)
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Reactivities
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Human (115), Mouse (Murine) (87), Rat (Rattus) (17)
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Applications
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Flow Cytometry (FACS) (155), Immunohistochemistry (Frozen Sections) (IHC (fro)) (46), Western Blotting (WB) (37), Enzyme Immunoassay (EIA) (20), Immunofluorescence (IF) (19), Immunoprecipitation (IP) (17), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (14), ELISA (8), Dot Blot (Dot) (4), ELISA (Detection) (3), Immunohistochemistry (IHC) (3), Immunocytochemistry (ICC) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Capture) (1), Functional Studies (Func) (1), Immunoelectron Microscopy (EM) (1), Radioimmunoassay (RIA) (1)
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Conjugates
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FITC (27), Biotin (14), PE (8), Cy5 (5), APC (3), Cy5.5 (3), RPE (3), SPRD (2), Alexa Flour 488 (1), Alexa Fluor 700 (1), Cy3 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), Pacific Blue (1), RBITC (1)
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