TP53AIP1
Reactivity: Human, Mouse
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
Cy5.5
Application Notes
Western Blot. Immunohistochemistry on Paraffin Sections (5 μg/mL). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.
Target
TP53AIP1
(P53-Regulated Apoptosis-Inducing Protein 1 (TP53AIP1))
Alternative Name
TP53AIP1
Background
P53AIP1 is located in mitochondria and its overexpression results in growth suppression and apoptosis. The induction of p53AIP1 transcription in response to DNA damage is dependent on phosphorylation of p53 at Ser-46. The p53AIP1 gene has 3 major transcripts, designated alpha, beta and gamma.Synonyms: p53-regulated apoptosis-inducing protein 1, p53AIP1