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LFC antibody
| Antigen | LFC |
| Clonality | Polyclonal |
| Host |
Sheep |
| Reactivity |
Mouse (Murine) |
| Application |
Western Blotting (WB)
|
| Catalog no. | ABIN306728 |
| Quantity | 250 ug (1 mg/ml) |
| Price | 210.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 to 7 Business Days |
Additional Information
| Isotype | IgG (Matching secondary antibodies) |
| Description | Lfc is a 118 kDa protein discovered in a screen for oncogenes in NIH 3T3 cells. Lfc is a signaling protein related to Lbc and is part of the Dbl family of proteins. Lfc is a guanine-nucleotide exchange factor (GEF) for the Rho family of small GTPases. Lfc has also been shown to be upstream of the serine-threonine kinase JNK. Lfc has also been shown to mediate the activation of the Rac signaling pathway. |
Application Details
| Application Notes | Detects Lfc in mouse tissues by immunoprecipitation-Western blot at 4 ug/ml. Detects a 118 kDa band in mouse tissue extracts corresponding to wild-type Lfc. Can also be used in immunofluorescence assays. |
| Concentration | 1 mg/ml |
| Storage | Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles |
| Restrictions | For Research Use only |
