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Antibody
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anti-SH3 Binding Protein 2 3BP2
SH3 Binding Protein 2 (3BP2) antibody
| Antigen |
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| Synonyms |
3BP2 |
| Clonality |
Polyclonal |
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Host
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Sheep
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Reactivity
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Mouse (Murine)
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Application
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Western Blotting (WB)
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| Catalog no. |
ABIN306729 |
| Quantity |
250 ug (1 mg/ml) |
| Price |
210.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 10 Business Days |
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Alternative name
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3BP2 (SH3 Binding Protein 2)
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Swiss-Prot
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Q06649
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Isotype
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IgG (Matching secondary antibodies)
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Description
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3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLC 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1. Mouse 3BP2 is 66% homologous to the human protein at the amino acid level. Synonyms: Sh3bp2, SH3 domain-binding protein 2.
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Application Notes
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Detects 3BP2 protein by Western blot analysis. Detects a 85 kDa band in murine fibroblasts transfected with 3BP2. Positive Control: Recombinant 3BP2 protein.
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Concentration
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1 mg/ml
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Storage
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Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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Restrictions
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For Research Use only
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