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SH3 Binding Protein 2 (3BP2) antibody
| Antigen | SH3 Binding Protein 2 (3BP2) |
| Synonyms | 3BP2 |
| Clonality | Polyclonal |
| Host |
Sheep |
| Reactivity |
Mouse (Murine) |
| Application |
Western Blotting (WB)
|
| Catalog no. | ABIN306729 |
| Quantity | 250 ug (1 mg/ml) |
| Price | 210.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 to 7 Business Days |
Additional Information
| Alternative name | 3BP2 (SH3 Binding Protein 2) |
| Swiss-Prot | Q06649 |
| Isotype | IgG (Matching secondary antibodies) |
| Description | 3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLC 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1. Mouse 3BP2 is 66% homologous to the human protein at the amino acid level. Synonyms: Sh3bp2, SH3 domain-binding protein 2. |
Application Details
| Application Notes | Detects 3BP2 protein by Western blot analysis. Detects a 85 kDa band in murine fibroblasts transfected with 3BP2. Positive Control: Recombinant 3BP2 protein. |
| Concentration | 1 mg/ml |
| Storage | Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles |
| Restrictions | For Research Use only |
