Kein 7 antibody

Catalog No. ABIN306824

The Mouse Monoclonal anti-Kein 7 antibody is suitable to detect Kein 7 in samples from Human. It has been validated for IHC (fro) and WB.

Quick Overview for Kein 7 antibody (ABIN306824)

Target: Kein 7

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)

Clone: C35

Product Details

Purpose: Mouse anti Human Keratin 7

Cross-Reactivity: Human

Characteristics: Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie., skin) and non-keratinizing cells (ie., mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. Atleast 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification. Cytokeratin 7 is a basic cytokeratin which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of the ovary, lung and breast but not colon or gastrointestinal tract.

Purification: Protein A/G Chromatography

Isotype: IgG1

Application Details

Application Notes: Detects keratin 7 by Western blot. Detects a 54 kDa band corresponding to keratin 7. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details

Target: Kein 7

UniProt: P08729