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Antibody
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anti-Adrenergic alpha-2B- Receptor ADRA2B
Adrenergic, alpha-2B-, Receptor (ADRA2B) antibody
| Antigen |
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| Synonyms |
zgc:194747, Adra2b, ADRA2L1, ADRARL1, ADRA2RL1, ALPHA2BAR, [a]2B, Adra-2b, alpha2B, alpha2-C2, ADRA2B |
| Clonality |
Monoclonal (5G10) |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN306933 |
| Quantity |
100 ug (1 mg/ml) |
| Price |
345.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 10 Business Days |
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Alternative name
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alpha2B Adrenergic Receptor
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Swiss-Prot
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P19328
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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5G10
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Description
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The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.
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Application Notes
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Antibody detects alpha2B Adrenergic Receptors (1-5 ug/ml) and immunohistochemistry. Positive Control: MDCK cells transfected with rat alpha2B adrenergic receptors..
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Concentration
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1 mg/ml
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Storage
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Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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Restrictions
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For Research Use only
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