LOR antibody (N-Term)

Catalog No. ABIN310215

Product Details anti-LOR Antibody

Target: LOR (Loricrin (LOR))

Binding Specificity: N-Term

Reactivity: Please inquire

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GYSGGGCGGG SSGGGGGGGI GGCGGGSGGS VKYSGGGGSS GGGSGCFSSG

Predicted Reactivity: Cow: 93%, Guinea Pig: 75%, Human: 100%, Mouse: 86%

Characteristics: This is a rabbit polyclonal antibody against LOR. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LOR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 316 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LOR

Target: LOR (Loricrin (LOR))

Alternative Name: LOR (LOR Products)

Target Type: Chemical

Background: LOR is a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.LOR encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in LOR may be the cause of both Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.
Alias Symbols: MGC111513
Protein Interaction Partner: EVPL, VIM, SPRR3, PI3, LOR, KRT1, IVL, CSTA,
Protein Size: 312

Molecular Weight: 26 kDa

Gene ID: 4014

NCBI Accession: NM_000427, NP_000418

UniProt: P23490