ROM1 antibody (Middle Region)

Catalog No. ABIN310578

Product Details anti-ROM1 Antibody

Target: ROM1 (Retinal Outer Segment Membrane Protein 1 (ROM1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ROM1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NPHSPRPCLQ NRLSDSYAHP LFDPRQPNQN LWAQGCHEVL LEHLQDLAGT

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ROM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ROM1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 351 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ROM1

Target: ROM1 (Retinal Outer Segment Membrane Protein 1 (ROM1))

Alternative Name: ROM1 (ROM1 Products)

Background: ROM1 is an integral membrane protein found in the photoreceptor disk rim of the eye. It can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa.This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ROM, ROSP1, TSPAN23, RP7
Protein Interaction Partner: PHGDH, PRPH2,
Protein Size: 351

Molecular Weight: 37 kDa

Gene ID: 6094

NCBI Accession: NM_000327, NP_000318

UniProt: Q03395