IGFBP7 antibody (C-Term)

Catalog No. ABIN310993

This Rabbit Polyclonal antibody specifically detects IGFBP7 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Sheep.

Quick Overview for IGFBP7 antibody (C-Term) (ABIN310993)

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFBP7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-IGFBP7 Antibody

Binding Specificity: C-Term

Sequence: RGGPEKHEVT GWVLVSPLSK EDAGEYECHA SNSQGQASAS AKITVVDALH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against IGFBP7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IGFBP7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 282 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IGFBP7

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Alternative Name: IGFBP7

Background: IGFBP7 contains 1 Ig-like C2-type (immunoglobulin-like) domain, 1 IGFBP N-terminal domain and 1 Kazal-like domain. It binds IGF-I and IGF-II with a relatively low affinity. IGFBP7 stimulates prostacyclin (PGI2) production.
Alias Symbols: FSTL2, IGFBP-7, IGFBP-7v, MAC25, PSF, AGM, TAF, IBP-7, RAMSVPS, IGFBPRP1
Protein Interaction Partner: RBBP8, HNF1A, RTN4, DSTN, UBC, CHMP3, CCL21, VEGFA, CCL5, SDC1, INS, IGF2, IGF1, CXCL10, INHBA,
Protein Size: 282

Molecular Weight: 29 kDa

Gene ID: 3490

NCBI Accession: NM_001553, NP_001544

UniProt: Q16270

Pathways: Growth Factor Binding