Transglutaminase 5 antibody (C-Term)
Quick Overview for Transglutaminase 5 antibody (C-Term) (ABIN311154)
Target
See all Transglutaminase 5 (TGM5) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- VLKPQHQASI ILETVPFKSG QRQIQANMRS NKFKDIKGYR NVYVDFAL
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Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 85%, Rat: 93%
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Characteristics
- This is a rabbit polyclonal antibody against TGM5. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human TGM5
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 720 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Transglutaminase 5 (TGM5)
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Alternative Name
- TGM5
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Background
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TGM5 belongs to the transglutaminase superfamily, transglutaminase family. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. It contributes to the formation of the cornified cell envelope of keratinocytes. Defects in TGM5 are a cause of peeling skin syndrome acral type (APSS).
Alias Symbols: MGC141907, TGM6, TGMX, TGX, TGASE5, TGASEX
Protein Interaction Partner: UBC,
Protein Size: 720 -
Molecular Weight
- 81 kDa
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Gene ID
- 9333
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NCBI Accession
- NM_201631, NP_963925
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UniProt
- O43548
Target
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