Sulfatase 2 (SULF2) antibody
| Antigen |
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| Synonyms |
HSULF-2, FLJ44488, FLJ90554, KIAA1247, MGC126411, DKFZp313E091, AU020235, mKIAA1247, 2010004N24Rik, Sulf1, MGC55612, zgc:55612, xtsulf2, SULF2, fb48e04, wu:fb48e04 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Chicken, Xenopus laevis
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Conjugate
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Application
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Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
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| Catalog no. |
ABIN311170 |
| Quantity |
0.1 mg |
| Price |
251.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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SULF2
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Gene ID
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SULF2
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UniProt
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Q8IWU5
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Immunogen
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The immunogen for anti-SULF2 antibody: synthetic peptide directed towards the C terminal of human SULF2
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Sequence
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DVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE QYRQFQRRKW
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Cross-Reactivity
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Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 100 µl of distilled water. Final anti-SULF2 antibody concentration is 1 mg/ml.
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Description
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Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM].
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Characteristics
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Antigen Size: 870 amino acids
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Molecular Weight
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98kDa
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Purification
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Protein A purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Restrictions
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For Research Use only
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Product
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Uchimura, Morimoto-Tomita, Bistrup et al.: "HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1." in: BMC biochemistry, Vol. 7, pp. 2, 2006 (PubMed).
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Alternatives for antigen "Sulfatase 2 (SULF2)", type "Antibodies"
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Hosts
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Rabbit (26), Goat (3)
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Reactivities
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Human (28), Mouse (Murine) (20), Chicken (19), Cow (Bovine) (19), Dog (Canine) (19), Pig (Porcine) (19), Rat (Rattus) (19)
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Applications
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Immunofluorescence (IF) (16), Western Blotting (WB) (13), ELISA (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1), Immunoprecipitation (IP) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Epitopes
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C-Term (2), Internal Region (1)
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2013 BioMed Central Research Awards
