Neuroligin Y antibody
| Antigen |
|
| Synonyms |
KIAA0951 |
| Clonality |
Polyclonal |
|
Host
|
|
|
Reactivity
|
 Alternatives Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Dog (Canine), Zebrafish, Chicken
|
|
Conjugate
|
Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
|
|
Application
|
|
| Catalog no. |
ABIN311201 |
| Quantity |
50 µg (Variants) |
| Price |
317.90 $ Plus shipping costs $45.00
|
|
Bulk discount
|
| Shipping to |
|
| Availability |
Will be delivered in 2 to 3 Business Days |
|
Gene ID
|
NLGN4X
|
|
UniProt
|
Q8NFZ3
|
|
Immunogen
|
The immunogen for anti-NLGN4X antibody: synthetic peptide directed towards the N terminal of human NLGN4X
|
|
Sequence
|
SILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQ IQALRWIEEN
|
|
Cross-Reactivity
|
Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)
|
|
Format
|
Lyophilized
|
|
Reconstitution
|
Add 50 µl of distilled water. Final anti-NLGN4X antibody concentration is 1 mg/ml.
|
|
Description
|
NLGN4X is a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. It interacts with discs, large (Drosophila) homolog 4 (DLG4). NLGN4X might play a role in the autism and Asperger syndrome.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests. This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene.
|
|
Characteristics
|
Antigen Size: 816 amino acids
|
|
Molecular Weight
|
92kDa
|
|
Application Notes
|
WB Suggested Anti-NLGN4X Antibody Titration: 0.2-1 ug/ml
Positive Control: Hela cell lysate.
|
|
Purification
|
Affinity Purified
|
|
Buffer
|
PBS
|
|
Storage (Long Term)
|
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
|
|
Storage (Short Term)
|
Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
|
|
Restrictions
|
For Research Use only
|
|
Product
|
Wermter, Kamp-Becker, Strauch et al.: "No evidence for involvement of genetic variants in the X-linked neuroligin genes NLGN3 and NLGN4X in probands with autism spectrum disorder on high functioning level." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 535-7, 2008 (PubMed).
|
Alternatives for antigen "Neuroligin Y", type "Antibodies"
|
Hosts
|
Rabbit (27), Mouse (1)
|
|
Reactivities
|
Human (28), Mouse (Murine) (3), Rat (Rattus) (3), Chicken (2), Cow (Bovine) (2), Dog (Canine) (2), Cat (Feline) (1), Xenopus laevis (1), Zebrafish (1)
|
|
Applications
|
Immunofluorescence (IF) (16), Western Blotting (WB) (13), ELISA (12), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1), Immunoprecipitation (IP) (1)
|
|
Conjugates
|
Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
|
|
Epitopes
|
N-Term (1), N-Term,AA 138-167 (1)
|
