Osteocalcin antibody

Catalog No. ABIN316667

The Mouse Monoclonal anti-Osteocalcin antibody is suitable to detect Osteocalcin in samples from Human, Rat, Rabbit, Cow and Pig. It has been validated for EIA.

Quick Overview for Osteocalcin antibody (ABIN316667)

Target: Osteocalcin (BGLAP)

Reactivity: Human, Rat, Rabbit, Cow, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This Osteocalcin antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: 3H8H12D2A12F12

Product Details anti-Osteocalcin Antibody

Specificity: This antibody recognizes intact human and bovine osteocalcin in a "2 site" assay and reacts with osteocalcin fragments corresponding to amino acids 15-31 and 20-43 of the native molecule. It does not recognize fragments representing amino acids 1-19 or 7-19 or intact bovine osteocalcin.

Characteristics: Synonyms: Bone Gla protein, BGLAP, Gamma-carboxyglutamic acid-containing protein

Purification: Purified IgG prepared by affinity chromatography on Protein A

Immunogen: Native bovine osteaocalcin

Isotype: IgG2a

Application Details

Application Notes: ELISA: This antibody may be used in combination with ABIN316666 or ABIN316665 insandwich ELISA assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % Sodium Azide (NaN3)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

Expiry Date: 12 months

Target Details for Osteocalcin

Target: Osteocalcin (BGLAP)

Alternative Name: Osteocalcin

Background: Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Pagets disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.Synonyms: BGLAP, Bone Gla protein, Gamma-carboxyglutamic acid-containing protein

Gene ID: 632

UniProt: P02818