HCV Core Protein antibody (AA 33-38)

Catalog No. ABIN317133

The Mouse Monoclonal anti-HCV Core Protein antibody (Clone 1868) (ABIN317133) specifically detects HCV Core Protein in WB, IF and EIA. The antibody is reactive with Hepatitis C Virus (HCV) samples.

Quick Overview for HCV Core Protein antibody (AA 33-38) (ABIN317133)

Target: HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))

Reactivity: Hepatitis C Virus (HCV)

Host: Mouse

Clonality: Monoclonal

Conjugate: This HCV Core Protein antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Clone: 1868

Product Details anti-HCV Core Protein Antibody

Binding Specificity: AA 33-38

Characteristics: Synonyms: Hepatitis C Virus

Purification: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant

Immunogen: Recombinant full-length core protein.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/20-1/200. Immunofluorescence: 1/10-1/50. Western Blot: 1/10-1/50. Detects a band of approximately 30 kDa.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: 0.01 M PBS, pH 7.2 containing 0,09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for HCV Core Protein

Target: HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))

Alternative Name: HCV Core Protein

Target Type: Viral Protein

Background: HCV is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural protein necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha. Hepatitis C virus (HCV) core protein is thought to contribute to HCV pathogenesis through its interaction with various signal transduction pathways. In addition, HCV core antigen is a recently developed marker of hepatitis C infection. The HCV core protein has been previously shown to circulate in the bloodstream of HCV-infected patients and inhibit host immunity through an interaction with gC1qR.Synonyms: Hepatitis C Virus core protein