GRP94 antibody (AA 676-803)

Catalog No. ABIN317571

The Mouse Monoclonal anti-GRP94 antibody is suitable to detect GRP94 in samples from Human. It has been validated for WB, IF, IHC (p) and EIA.

Quick Overview for GRP94 antibody (AA 676-803) (ABIN317571)

Target: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GRP94 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 2H3

Product Details anti-GRP94 Antibody

Binding Specificity: AA 676-803

Specificity: The antibody recognizes Human TRA1. Other species not tested.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: Tumor rejection antigen 1, GRP94, Heat shock protein 90 kDa beta member 1, 94 kDaglucose-regulated protein

Purification: Protein-G affinity chromatography

Immunogen: Recombinant Human TRA1 (676-803 aa) purified from E. coli

Isotype: IgG2a

Application Details

Application Notes: ELISA. Western blot. Immunofluorescence (1/100-1/200). Immunohistochemistry on Paraffin Sections (5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for GRP94

Target: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Alternative Name: Endoplasmin / HSP90B1 / TRA1

Background: Tumor rejection antigen 1 (TRA1) is expressed on the surface of human teratocarcinoma stem cells (EC), human embryonic germ cells (EG) and human embryonic stem cells (ES). TRA1 is a marker protein of these stem cells.Synonyms: 94 kDa glucose-regulated protein, GRP94, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1

Gene ID: 7184

UniProt: P14625

Pathways: Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades