CNR2 antibody
Quick Overview for CNR2 antibody (ABIN317647)
Target
See all CNR2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- This antibody detects endogenous levels of Cannabinoid Receptor 2 (CB2) protein.(region surrounding Arg334)
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Purification
- Affinity Chromatography using epitope-specific immunogen.
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Application Notes
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ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CNR2 (Cannabinoid Receptor 2 (CNR2))
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Alternative Name
- Cannabinoid Receptor 2
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Background
- The cannabinoid receptors (CB1 and CB2) are G protein-coupled receptors that inhibit adenylate cyclase activity in response to psychoactive cannabinoids.CB1 is expressed in brain tissue and, in low levels, in testis. CB2 is expressed only by cells of the immune system. The cannabinoid receptors mediate most of the cannabinoid-induced responses in a dose-dependent, stereoselective manner. This response system is thought to be involved in specific brain functions, such as nociception, control of movement, memory and neuroendocrine regulation, as well as having a possible role in brain development. In addition, CB1 may mediate the addictive behavior involved with the use of psychoactive cannabinoids, such as THC in marijuana.Synonyms: CB-2, CB2, CNR2, CX5, hCB2
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Gene ID
- 1269
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NCBI Accession
- NP_001832
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UniProt
- P34972
Target
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