TFAP2C antibody

Catalog No. ABIN317676

The Rabbit Polyclonal anti-TFAP2C antibody (ABIN317676) specifically detects TFAP2C in WB and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TFAP2C antibody (ABIN317676)

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFAP2C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TFAP2C Antibody

Specificity: This antibody detects endogenous levels of AP-2 gamma protein.(region surrounding Ala436)

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1/40000-1/60000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TFAP2C

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Alternative Name: AP2-gamma / TFAP2C

Background: AP2 gamma is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.Synonyms: Activating enhancer-binding protein 2 gamma, ERF-1, ERF1, Transcription factor AP2 gamma, Transcription factor ERF-1

Molecular Weight: approx. 45 kDa

Gene ID: 7022

NCBI Accession: NP_003213

UniProt: Q92754

Pathways: Stem Cell Maintenance