Adenosine A2a Receptor (ADORA2A) antibody

Antigen: Adenosine A2a Receptor (ADORA2A)

Synonyms: ADORA2A, adora2a.1, zgc:194773, LOC606744, LOC100034039, Adora2a, RDC8, hA2aR, ADORA2, A2aR, A2AAR, AA2AR, MGC118414, A2ar, ADENO, Adora2l1, MGC93190

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Catalog no.: ABIN317694

Additional Information

Characteristics: Synonyms: ADORA2A, ADORA2

Alternative name: Adenosine receptor A2a

Swiss-Prot: P29274

Cross-Reactivity: Human

Description: Adenosine is involved in a variety of processes, including the synthesis of urea, theanti-inflammatory response and the inhibition of protein synthesis. The adenosinereceptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and AdenosineA3-R, are integral membrane proteins that are members of the G protein-coupled receptorfamily. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagensynthasis and total protein synthesis are inhibited in certain cells by adenosine, acting viathe A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokineTNFα and blocks the endotoxin CD14 receptor signal transduction pathway.

Specificity: This antibody detects endogenous levels of Adenosine A2A-R protein. Species Reactivity: Tested: Human. Add. Information: Molecular Weight: ~45 kDa

Application Details

Application Notes: ELISA: 1/1000~1/10000. Western Blot: 1/500~1/1000. Immunohistochemistry: 1/50~1/200. Immunofluorescence: 1/50~1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 1.0 mg/ml

Purification: Aff - Purified

Buffer: Phosphate buffered saline (PBS), pH~7.2 containing 0.05% Sodium Azideas preservative.

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Research Area: Cell Cycle, DNA/RNA, Receptors

Restrictions: For Research Use only