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Antibodies
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anti-Adenosine A1 Receptor (ADORA1) antibody
Adenosine A1 Receptor (ADORA1) antibody
| Antigen |
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| Synonyms |
RDC7, Ri, A1R, A1AR, AA1R, A1-AR, AI848715, BB176431, ADORA1, adora1-A, a1R, LOC606743, Adora1, DKFZp469D1021, LOC100222054, LOC100328615 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Enzyme Immunoassay (EIA), Western Blotting (WB)
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| Catalog no. |
ABIN317738 |
| Quantity |
100 µg (1.0 mg/ml) (Variants) |
| Price |
340.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: ADORA1
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Alternative name
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Adenosine receptor A1
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Swiss-Prot
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P30542
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Cross-Reactivity
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Human, Rat (Rattus)
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Description
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Adenosine is involved in a variety of processes, including the synthesis of urea, theanti-inflammatory response, and the inhibition of protein synthesis. The Adenosinereceptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and AdenosineA3-R, are integral membrane proteins that are members of the G protein-coupled receptorfamily. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagensynthasis and total protein synthesis are inhibited in certain cells by Adenosine, acting viathe A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokineTNFα and blocks the endotoxin CD14 receptor signal transduction pathway.
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Specificity
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This antibody detects endogenous levels of Adenosine A1-R protein. Species: Human and Rat. Others not tested.
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Application Notes
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ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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1.0 mg/ml
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Purification
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Aff - Purified
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Buffer
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Phosphate buffered saline (PBS), pH~7.2 containing 15 mM Sodium Azideas preservative.
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Cell Cycle, DNA/RNA, Receptors
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Restrictions
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For Research Use only
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Alternatives for antigen "Adenosine A1 Receptor (ADORA1)", type "Antibodies"
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Hosts
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Rabbit (29), Goat (3)
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Reactivities
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Human (27), Rat (Rattus) (26), Mouse (Murine) (25), Cow (Bovine) (4), Dog (Canine) (1), Pig (Porcine) (1)
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Applications
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Flow Cytometry (FACS) (18), Immunofluorescence (IF) (18), Western Blotting (WB) (9), ELISA (6), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunoprecipitation (IP) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Enzyme Immunoassay (EIA) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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C-Term (1)
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