EMR4P antibody

Catalog No. ABIN317748

The Rabbit Polyclonal anti-EMR4P antibody (ABIN317748) specifically detects EMR4P in WB, IF and EIA. The antibody is reactive with Human samples.

Quick Overview for EMR4P antibody (ABIN317748)

Target: EMR4P (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 4 Pseudogene (EMR4P))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EMR4P antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-EMR4P Antibody

Specificity: EMR4 antibody detects endogenous levels of EMR4 protein.(region surrounding Ile140)

Purification: Affinity-chromatography

Application Details

Application Notes: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for EMR4P

Target: EMR4P (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 4 Pseudogene (EMR4P))

Alternative Name: EMR4P / GPR127

Background: FIRE is a 689 amino acid protein that maps to human gene EMR4. FIRE is also known as EGF-like module-containing mucin-like hormone receptor-like 4 and is a member of the the G protein-coupled receptor 2 family, LN-TM7 subfamily. The epidermal growth factor-transmembrane seven (EGF-TM7) family are proteins that express EGF-like domains at their extracellular N-terminus coupled to a classical seven-transmembrane (TM7) cassette. FIRE is believed to mediate the cellular interaction between myeloid cells and β cells. FIRE is a membrane bound, multi-pass protein that is proteolytically cleaved into two subunits, an extracellular α subunit and a seven-transmembrane subunit. FIRE contains one GPS (G protein-coupled receptor proteolytic cleavage site) domain and two EGF (epidermal growth factor)-like domains, the second of which mediates the interaction with the putative ligand.Synonyms: G-protein coupled receptor 127, G-protein coupled receptor PGR16, Putative EGF-like module-containing mucin-like hormone receptor-like 4

Molecular Weight: approx. 55 kDa

Gene ID: 9606

UniProt: Q86SQ3