INSL4 antibody

Catalog No. ABIN317832

The Rabbit Polyclonal anti-INSL4 antibody (ABIN317832) specifically detects INSL4 in WB, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for INSL4 antibody (ABIN317832)

Target: INSL4 (Insulin-Like 4 (Placenta) (INSL4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSL4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-INSL4 Antibody

Specificity: INSL4 antibody detects endogenous levels of INSL4 protein.(region surrounding Leu79)

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for INSL4

Target: INSL4 (Insulin-Like 4 (Placenta) (INSL4))

Alternative Name: INSL4 / EPIL

Background: Insulin is a secreted peptide hormone that elicits metabolic effects such as increases in glucose uptake and glycogen synthesis leading to a decrease in blood glucose concentration. Insulin is first formed as a precursor molecule, preproinsulin, which is later cleaved to proinsulin and finally to the mature insulin hormone. Insulin-like peptides (INSL proteins), also designated Relaxinlike factors, are members of the insulin family, which regulate cell growth, metabolism and tissue-specific functions. INSL1-7 are mostly secreted proteins that are expressed mainly in testis, placenta, uterus or prenatal tissues. INSL4 is a 139 amino acid secreted protein expressed in the placenta, uterus and in fetal perichondrium. It may play an important role in the regulation of bone formation and in trophoblast development.Synonyms: Early placenta insulin-like peptide, Insulin-like peptide 4, Placentin

Molecular Weight: approx. 19 kDa

Gene ID: 3641

NCBI Accession: NP_002186

UniProt: Q14641